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3536 : Combination of Dexamethasone and Asparaginase Induces Prothrombotic State in Children Receiving Multiagent Chemotherapy for Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Anthony K.C. Chan

Principal Investigators

  • Uma Athale

Medical Centers

  • McMaster Childrens Hospital at Hamilton Health Sciences, Hamilton, ON, Canada

  • Division of Pediatric Hematology/ Oncology, McMaster University, Hamilton, Canada

  • McMaster University, Hamilton, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Venous thrombosis

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Plasminogen activator ihnibitor-1

  • D-dimer

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Asparaginase

  • Hemostatic Solution

  • Protein C

  • Evithrom

  • Grace

  • FVIII

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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