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3528 : Prednisolone Resistance in Pediatric Acute Lymphoblastic Leukemia Can Be Synergistically Overcome by Inhibition of Anti-Apoptotic MCL1 and Glycolysis

Researchers

Presenter

  • Bo R. Hansen

Principal Investigators

  • Troels Koch

  • William E. Evans

  • Rob Pieters

  • Monique L. den Boer

Medical Centers

  • Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands

Locations

  • Netherlands

Companies

  • Santaris Pharma A/S

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Acute lymphoblastic leukemia

  • Tuberculosis

Biomarkers

  • B-cell lymphoma 2

  • Breakpoint Cluster Region

Drug/Treatment

  • 2-deoxyglucose

  • Prednisolone

  • 2-Deoxy-D-Glucose

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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