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2984 : Lentivirally Transduced Human Cord Blood CD34+FLT3-ITD+ Cells Induce Murine Acute Leukemia in the NOD/SCID Transplantation Model.

Researchers

Presenter

  • Doris Steinemann

Principal Investigators

  • Rama Krishna Kancha

  • Leticia Quantanilla-Fend

  • Stefan K Bohlander

  • Christian Peschel

  • Robert A.J. Oostendorp

  • Christopher Baum

  • Katharina S. Goetze

Medical Centers

  • Department of Internal Medicine III, Technical University of Munich, Munich, Germany

  • Center for Human Genetics, Philipps University Marburg, Marburg, Germany

  • Department of Experimental Hematology, Hannover Medical School, Hannover, Germany

  • Insitute of Physiology 2, Eberhard Karls Universitat Tubingen, Tubingen, Germany

  • Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany, Hannover, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Acute Leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 34

  • Cluster of differentiation 45

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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