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2906 : Phenethyl Isothiocyanate (PEITC) Regulates Autophagy in Chronic Lymphocytic Leukemia.

Researchers

Presenter

  • R Gitendra Wickremasinghe

Principal Investigators

  • Archibald G Prentice

  • Jonathan C. Strefford

  • Andrew Duncombe

  • Francesco Forconi

  • Freda K. Stevenson

  • Graham Packham

  • Andrew Steele

Medical Centers

  • Cancer Sciences, University of Southampton, Southampton, United Kingdom

  • Cancer Sciences, University of Southampton, Southampton, United Kingdom

  • Cancer Sciences, University of Southampton, Southampton, United Kingdom

  • Dept of Haematology, Southampton Univ Hospt, Southampton, United Kingdom

  • The Royal Marsden Hospital, London, United Kingdom

  • Department of Haematological Medicine, King's College London, London, United Kingdom

  • Cancer Sciences, University of Southampton, Southampton, United Kingdom

  • Cancer Sciences, University of Southampton, Southampton, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Chronic Lymphocytic Leukemia

Biomarkers

  • Annexin V

  • Autophagy-related gene 5

  • B-cell lymphoma 2

  • Beclin-1

  • C-C Motif Chemokine Ligand 22

  • Proto-oncogene tyrosine-protein kinase ROS

  • Interleukin 1 alpha

Drug/Treatment

  • Phenethyl isothiocyanate

  • Hydroxychloroquine

  • ribose

  • ATG3

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • NCT00968461

Sponsors

  • N/A

Result

  • Interim

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