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3193 : CH50 Activity Correlates with Residual Intravascular Hemolysis in Pts with Paroxysmal Nocturnal Hemoglobinuria Treated by Eculizumab

Researchers

Presenter

  • Veronique Fremeaux-Bacchi

Principal Investigators

  • Raphael Porcher

  • Paula Rodriguez-Otero

  • Stephane Roncellin

  • Sarah Abbes

  • Gerard Socie

Medical Centers

  • Hematology and Bone Marrow Transplantation, Saint-Louis Hospital, Paris, France,

  • Hematologie-Greffe, AP-HP, Hopital Saint-Louis, Paris, France

  • biostatistics Saint Louis Hospital, paris, France

  • Service dimmunologie Biologique, Hopital Georges Pompidou, Paris, France

Locations

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Paroxysmal nocturnal hemoglobinuria

  • Deep vein thrombosis

  • Complement factor H deficiency

  • Aplastic anemia

  • Complement component 5 deficiency

  • Venous thrombosis

  • Anemia

Biomarkers

  • Lactate dehydrogenase

  • Red Blood Cells

  • Total complement hemolytic activity

Drug/Treatment

  • Eculizumab

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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