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3303 : A Small Molecule Inhibitor of the Gas6/Mer Pathway Inhibits Platelet Activation and Thrombosis with Equal Efficacy to, but Greater Potency Than, iMer, the Novel MerTK Splice Variant

Researchers

Presenter

  • Luke Law

Principal Investigators

  • Susan Sather

  • Gary Brodsky

  • H. Shelton Earp III

  • Xiaodong Wang

  • Stephen Frye

  • Douglas K. Graham

  • Jorge A Di Paola

Medical Centers

  • Department of Pediatrics, University of Colorado/Childrens Hospital Colorado, Aurora, CO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Pulmonary embolism

  • Venous thrombosis

Biomarkers

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Hepatocyte growth factor receptor

Drug/Treatment

  • Adrenaclick

  • Abciximab

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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