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3889 : The Pro-Inflammatory IL23/IL23R/IL17 Axis Is Active in IL23R-Expressing Circulating CLL Cells in Patients with Poor Prognosis

Researchers

Presenter

  • Giovanna Cutrona

Principal Investigators

  • Anna Grazia Recchia

  • Caterina Musolino

  • Fiorella Ilariucci

  • Gianluca Festini

  • Francesco Di Raimondo

  • Pierfrancesco Tassone

  • Antonino Neri

  • Claudio Tripodo

  • Manlio Ferrarini

  • Sonia Fabris

  • Serena Matis

  • Monica Colombo

  • Sabrina Bossio

  • Massimo Gentile

  • Carlotta Massucco

  • Laura De Stefano

  • Stefano Molica

Medical Centers

  • Rheumatology, University of Messina, Messina, Italy

  • Direzione Scientifica, Istituto Nazionale per la Ricerca sul Cancro, IST, Genova, Italy,

  • Medical Oncology, Magna Graecia University and T. Campanella Cancer Center, Salvatore Venuta Campus, Catanzaro, Italy

  • Oncohematology Division, Fondazione Ca Granda IRCCS Ospedale Maggiore Policlinico and University of Milan, Milano, Italy

  • Centro di Riferimento Ematologico-Seconda Medicina, Azienda Ospedaliero-Universitaria, Ospedali Riuniti, Trieste, Italy

  • Hematology-Oncology, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy

  • SS DIagnostica Molecolare, National Institute for Cancer Research, IST, Genova, Italy

  • U.O Direzione Scientifica, IRCCS AO Universitaria San Martino-IST, Genova, Italy

  • Oncoematologia, Ospedale Annunziata di Cosenza, Cosenza, Italy

  • Hematology Unit, Ferrarotto Hospital, Catania, Italy

  • Oncoematologia, Ospedale Annunziata di Cosenza, Cosenza, Italy

  • Medical Oncology C Department, National Institute for Cancer Research, IST, Genova, Italy

  • Department of Health Sciences, Human Pathology Section, University of Palermo, Palermo, Italy

  • Dipartimento Scienze Mediche - Ematologia CTMO, Universita di Milano -Fondazione Ca Granda Ospedale Maggiore IRCCS Policlinico, Milano, Italy

  • Hematology Unit, S.Maria Nuova Hospital, IRCCS, Reggio Emilia, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Lymphocytic Leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 38

  • Zeta-chain-associated protein kinase 70

Drug/Treatment

  • ZAP70

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • NCT00917540

Sponsors

  • N/A

Result

  • Interim

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