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2601 : Treating Ph+ Acute Lymphoblastic Leukemia (ALL) in the Elderly: The Sequence of Two Tyrosine Kinase Inhibitors (TKI) (Nilotinib and Imatinib) Does Not Prevent Mutations and Relapse.

Researchers

Presenter

  • Paola Fazi

Principal Investigators

  • Giorgina Specchia

  • Emanuele Angelucci

  • Monica Bocchia

  • Renato Fanin

  • Giuseppe Saglio

  • Daniele Vallisa

  • Sandra De Simone

  • Antonella Vitale

  • Ilaria Iacobucci

  • Simona Soverini

  • Francesco Di Raimondo

  • Anna Ferrari

  • Claudia Venturi

  • Caterina De Benedittis

  • Nicoletta Testoni

  • Antonio Curti

  • Stefania Paolini

  • Miriam Fogli

  • Giovanni Martinelli

  • Michele Baccarani

  • Giovanni Pizzolo

  • Angelo Michele Carella

  • Mario Cazzola

  • Antonio Cuneo

  • Pietro Leoni

  • Mario Luppi

  • Enrica Morra

Medical Centers

  • Department of Hematology, University of Ferrara, Ferrara, Italy

  • U.O.C. Ematologia 1, IRCCS A.O.U. San Martino-IST, Genova, Italy

  • Hematology Unit, Guglielmo da Saliceto Hospital, Piacenza, Italy

  • Department of Hematology/Oncology, University of Bologna, Bologna, Italy

  • Department of Hematology Oncology, IRCCS Policlinico S. Matteo Foundation and University of Pavia, Pavia, Italy

  • Sezione di Ematologia, University of Medicine of Verona, Dip. Medicina, Policlinico G.B. Rossi, Verona, Italy

  • GIMEMA, Rome, Italy

  • Bone Marrow Transplant Unit, Department of Oncology and Hematology, University of Modena, Modena, Italy

  • Haematological Clinic, Azienda Ospedaliera Universitaria, Udine, Italy

  • Oncology and Hematology, Niguarda Ca Granda Hospital, Milan, Italy

  • Department of Hematology, University of Torino, Torino, Italy

  • Department of Urology, University of Catania,Catania, Italy

  • Chair of Hematology, Department of Clinical and Biological Sciences S. Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy

  • Hematology and Bone Marrow Transplantation Unit, Ospedale Oncologico Armando Businco, Cagliari, Italy

  • Clinica di Ematologia Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Ancona, Ancona, Italy

  • Division of Hematology, University of Turin, Turin, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Nilotinib

  • Ponatinib

  • dasatinib

  • Imatinib

  • IkT001

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • NCT01025505

Sponsors

  • N/A

Result

  • Interim

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