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2607 : Evaluation of UNC569, a Novel Small Molecule Mer Inhibitor for the Treatment of ALL in Vitro and in Vivo.

Researchers

Presenter

  • Deborah DeRyckere

Principal Investigators

  • Jennifer Schlegel

  • Chao Yang

  • Catherine Simpson

  • Jacqueline Norris-Drouin

  • Stephen Frye

  • H. Shelton Earp III

  • Gary L. Johnson

  • Douglas K. Graham

  • Susan Sather

  • Amy McGranahan

  • J. Kimble Franzer

  • Alesia Trakhimets

  • Xiaodong Wang

  • Dmitri Kireev

  • William Janzen

  • Jing Liu

Medical Centers

  • Dept. of Pediatrics, Hematology/Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

  • Division of Medicinal Chemistry and Natural Products and Department of Medicine and Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • cMYC

  • Hepatocyte growth factor receptor

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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