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2578 : Modulation of Leukemic Stem Cell Self-Renewal and Cell Fate Decisions by Inhibition of Hedgehog Signalling in Human Acute Lymphoblastic Leukemia (ALL).

Researchers

Presenter

  • Susanne Badura

Principal Investigators

  • Martin Ruthardt

  • Michael A. Rieger

  • Oliver G. Ottmann

Medical Centers

  • Department of Medicine, Hematology/Oncology, Goethe University of Frankfurt, Frankfurt, Germany

  • Biomedical Research Institute, Georg Speyer Haus, Frankfurt Main, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Annexin V

  • B-lymphocyte antigen CD20

  • Breakpoint Cluster Region

  • Cluster of Differentiation 34

  • Cluster of Differentiation 38

Drug/Treatment

  • BMS-833923

  • Sonidegib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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