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2497 : Loss of Heterozygosity At the C Wild-Type Allele of rs1042522 in the TP53 Gene Frequently Occurs During Progression of Adult BCR-ABL1 Positive Acute Lymphoblastic Leukemia (ALL).

Researchers

Presenter

  • Anna Ferrari

Principal Investigators

  • Sarah Parisi

  • Federica Cattina

  • Simona Soverini

  • Domenico Russo

  • Fabrizio Pane

  • Robin Foa

  • Mario Luppi

  • Torsten Haferlach

  • Michele Baccarani

  • Giovanni Martinelli

  • Cristina Papayannidis

  • Claudia Venturi

  • Margherita Perricone

  • Maria Chiara Fontana

  • Paola Bresciani

  • Sabina Chiaretti

  • Mariachiara Abbenante

  • Stefania Paolini

Medical Centers

  • Munich Leukemia Laboratory, Munich, Germany.

  • CEINGE Biotecnologie Avanzate, Naples, Italy

  • Bone Marrow Transplant Unit, Department of Oncology and Hematology, University of Modena, Modena, Italy

  • Hematology, University of Brescia, Brescia, Italy

  • Department of Cellular Biotechnologies and Hematology, Sapienza University of Rome, Rome, Italy

  • Department of Hematology/Oncology, University of Bologna, Bologna, Italy

Locations

  • Germany

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • p53

  • Histone-lysine N-methyltransferase 2A

  • Tumor protein p53

Drug/Treatment

  • EXON 8

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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