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2371 : Karyotypic and Genetic Abnormalities Associated with Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria.

Researchers

Presenter

  • Kenichi Yoshida

Principal Investigators

  • Michael J. Clemente

  • Jaroslaw P. Maciejewski

  • Masashi Sanada

  • Yasunobu Nagata

  • Manuel G. Afable II

  • Andres Jerez

  • Kenichi Chiba

  • Yuichi Shiraishi

  • Satoru Miyano

  • Seishi Ogawa

Medical Centers

  • Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

  • Cancer Genomics Project, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

  • Laboratory of DNA information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Locations

  • United States

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Paroxysmal nocturnal hemoglobinuria

  • Aplastic anemia

  • Venous thrombosis

  • Anemia

Biomarkers

  • Glycosylphosphatidylinositol

  • High Mobility Group AT-Hook 2

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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