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2518 : CRLF2 Rearrangement Is Not Associated with Activated mTOR Pathway in NOD/SCID/huALL Xenograft Mouse Model.

Researchers

Presenter

  • Silvia Bresolin

Principal Investigators

  • Ilaria Bronzini

  • Chiara Palmi

  • Manon Queudeville

  • Sarah Mirjam Eckhoff

  • Luca Trentin

  • Giovanni Cazzaniga

  • Geertury te Kronnie

  • Klaus-Michael Debatin

  • Luder-Hinrich Meyer

Medical Centers

  • Centro Ricerca Tettamanti, Pediatric Clinic Univ. Milan Bicocca, Monza, Italy

  • Department of Womens and Childrens Health, Laboratory of Oncohematology, University of Padua, Padua, Italy

  • Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany

Locations

  • Germany

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Immunoglobulin heavy-chain variable region gene

Drug/Treatment

  • NVP-BEZ235

  • Rapacan

  • Cysteine Hydrochloride

  • BEZ235

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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