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116 : Hydroxychloroquine-Induced Cardiomyopathy in Systemic Lupus Erythematosus

Researchers

Presenter

  • Dafna Gladman

Principal Investigators

  • Paula Harvey

  • Susanna Mak

  • Kristy Yap

  • Chantal Morel

  • Jagdish Butany

Medical Centers

  • Division of Cardiology, Women's College Hospital, Toronto,Canada

  • Pathology Dept., Toronto General Hospital, Toronto,Canada

  • Fred A. Litwin Family Centre in Genetic Medicine, Mount Sinai Hospital, Toronto,Canada

  • Univ of Toronto, Toronto, Canada

  • Mecklinger Family and Posluns Family Cardiac Catheterization Research Laboratory, Mount Sinai Hospital, Toronto,Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Lupus

  • Left ventricular hypertrophy

  • Hypertrophic cardiomyopathy

  • Restrictive cardiomyopathy

  • Antiphospholipid syndrome

  • Left bundle branch block

  • Pulmonary arterial hypertension

  • Systolic dysfunction

  • Progressive cardiac conduction defect

  • Vitamin B12 deficiency anaemia

  • Ischemic stroke

  • Heart muscle disease

  • Hypothyroidism

  • Congestive heart failure

  • Fabry disease

  • Arrhythmia

  • Hypertension

  • Infective endocarditis

  • Pericarditis

  • Diabetic retinopathy

  • Cap myopathy

  • Dyspnea

  • Anemia

  • Stroke

Biomarkers

  • N-terminal pro b-type natriuretic peptide

Drug/Treatment

  • alpha-galactosidase

  • Hydroxychloroquine

  • Levothyroxine

  • chloroquine

  • Prednisone

  • Warfarin

Outcome

  • Unknown

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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