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1036 : Association of HER2 alterations and ESR1 mutations in cell-free DNA (cfDNA) with circulating tumor cells (CTCs), multiple metastasis, and prognosis in stage III/IV breast cancer (BCa).

Researchers

Presenter

  • Qiang Zhang

Principal Investigators

  • Lorenzo Gerratana

  • Ami N. Shah

  • Andrew A. Davis

  • Lisa E. Flaum

  • Youbin Zhang

  • Wenan Qiang

  • Amir Behdad

  • William John Gradishar

  • Leonidas C. Platanias

  • Massimo Cristofanilli

Medical Centers

  • Northwestern University, Department of Medicine, Division of Hematology/Oncology, Chicago, IL

  • University of Udine, Udine, Italy, Chicago, IL

  • Northwestern University, Chicago, IL

  • Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Chicago, IL

  • Department of Medicine, Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL

  • Northwestern University, Department of Medicine, Division of Hematology/Oncology, Chicago, IL

  • Northwestern University, Chicago, IL

  • Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL

  • Robert H. Lurie Cancer Center of Northwestern University, Chicago, IL

  • Robert H. Lurie Cancer Center of Northwestern University, Feinberg School of Medicine, Chicago, IL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • Circulating tumor cells

  • erb-b2 receptor tyrosine kinase 2

  • Estrogen Receptor 1

  • Plasma cell-free DNA

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final