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GW25-e0251 : Genetic polymorphisms of CYP2C19*2 and ABCB1 C3435T affect the pharmacokinetics and pharmacodynamics response to clopidogrel in patients with acute coronary syndrome in the Chinese Han population

Researchers

Presenter

  • Wang Xiaqin

Principal Investigators

  • Wang Bangnin

Medical Centers

  • the First Affiliated Hospital, Ganzhou Medical University, Ganzhou,China

  • the Fourth Affiliated Hospital, Anhui Medical University,China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Acute Coronary Syndromes

  • Venous thrombosis

Biomarkers

  • ATP Binding Cassette Transporter B1

  • Paraoxonase 1

  • Cytochrome P450 Family 3 Subfamily A Member 4

  • Cytochrome P450 Family 3 Subfamily A Member 5

  • Cytochrome P450 2C19

Drug/Treatment

  • Clopidogrel bisulfate

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim