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FRI0274 : HYDROXYCHLOROQUINE DOWN-REGULATES INTERFERON-ALFA ELEVATION THROUGH TLR-9 RECOGNITION OF NUCLEOTIDES WHICH IS IRRESPONSIVE TO GLUCOCORTICOID

Researchers

Presenter

  • O. Jin

Principal Investigators

  • X. zhang

  • L. Fang

  • Q. Li

  • H. Huang

  • Q. Wei

  • Z. Lin

  • Z. Liao

  • D. Lin

  • J. Gu

Medical Centers

  • Division of Rheumatology, Affiliated rd Hospital of Sun Yat-san University, Guangzhou, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Lupus

Biomarkers

  • Myeloid differentiation factor 88

  • Peripheral blood mononuclear cell

  • JunB proto-oncogene, AP-1 transcription factor subunit

Drug/Treatment

  • Hydroxychloroquine

  • Hydrocortisone

  • Glucocorticoid

  • Interferon

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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