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156 : Whole-Exome Sequencing Of Adult Philadephia-Negative Acute Lymphoblastic Leukemia From Diagnosis To Relapse After Allogeneic Hematopoietic Stem Cell Transplantation Reveals Clonal Evolution and Relapse-Associated Mutated Genes

Researchers

Presenter

  • Haowen Xiao

Principal Investigators

  • Yi Luo

  • Xiaoyu Lai

  • Xiujin Ye

  • Xiaohong Yu

  • Zhen Cai

  • He Huang

  • Jimin Shi

  • Yamin Tan

  • Jingsong He

  • Wanzhuo Xie

  • Weiyan Zheng

  • Li-Mengmeng Wang

  • Shan Fu

  • Yebo Wang

Medical Centers

  • Cancer Biotherapy Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China

  • Bone Marrow Transplantation Center, , the First Affiliated Hospital, Zhejiang University School of Medicine,

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

  • Philadelphia chromosome–positive (Ph+) ALL

Biomarkers

  • Ph chromosome

  • CREB-binding protein

  • Histone-lysine N-methyltransferase 2A

  • KRAS proto-oncogene, GTPase

Drug/Treatment

  • Allopurinol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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