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72 : Identification Of BCL6 As a Therapeutic Target In MLL-Rearranged ALL

Researchers

Presenter

  • Christian Hurtz

Principal Investigators

  • Huimin Geng

  • Erica Ballabio

  • Gang Xiao

  • Carina Ng

  • Behzad Kharabi Masouleh

  • Cheryl L. Willman

  • Scott A. Armstrong

  • Thomas Milne

  • Ari Melnick

  • Markus Muschen

Medical Centers

  • MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY

  • Department of Medicine/Hematology-Oncology and Department of Pharmacology, Weill Cornell Medical College, New York, NY

  • University of New Mexico Cancer Center, Albuquerque, NM

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

  • Acute lymphoblastic leukemia

  • B cell lymphomas

  • Lymphomas

  • Philadelphia chromosome–positive (Ph+) ALL

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Paired box 5

  • Cluster of Differentiation 19

  • Cyclin dependent kinase inhibitor 1B

  • White Blood Cell

Drug/Treatment

  • Vincristine

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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