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60 : HLA-DRB1*07:01 Is Associated With Asparaginase Allergies In Children With Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Christian A. Fernandez

Principal Investigators

  • Colton Smith

  • Elizabeth A. Raetz

  • Naomi J. Winick

  • Stephen P. Hunger

  • William L. Carroll

  • Suna Onengut-Gumuscu

  • Wei-Min Chen

  • Patrick Concannon

  • Stephen S Rich

  • Paul Scheet

  • Sima Jeha

  • Wenjian Yang

  • Ching-Hon Pui

  • William E. Evans

  • Meenakshi Devidas

  • Eric C. Larsen

  • W. Paul Bowman

  • Chengcheng Liu

  • Laura B. Ramsey

  • Tamara Chang

  • Victoria Turner

  • Mignon L. Loh

Medical Centers

  • Pediatric Hem./Onc./BMT, Univ. of Colorado School of Medicine, Aurora, CO

  • Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN

  • Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Neonatology, Benioff Childrens Hospital, University of California San Francisco, San Francisco, CA

  • Dept of Biostatistics, Colleges of Medicine, Public Health & Health Professions, University of Florida, Gainsville, FL

  • Pediatric Hematology/Oncology, NYU Cancer Institute, New York, NY

  • Maine Childrens Cancer Program, Scarborough, ME

  • Cancer Institute, New York University, New York, NY

  • Hematology and Oncology, St. Jude Childrens Research Hospital, Memphis, TN

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Radiology, Cook Childrens Medical Center, Fort Worth, TX

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Major Histocompatibility Complex, Class II, DQ Beta 1

  • Major histocompatibility complex, class II, DR beta 1

  • Thiopurine S-methyltransferase

Drug/Treatment

  • Asparaginase

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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