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25 : Blocking Protein S To Treat Hemophilia A

Researchers

Presenter

  • Luca Bologna

Principal Investigators

  • Sara Calzavarini

  • Francois Saller

  • Anne Angelillo-Scherrer

Medical Centers

  • Universitatsklinik fur Hamatologie und hamatologisches Zentrallabor, Inselspital, Bern, Switzerland

  • Hematology, University of Bern and Bern University Hospital, Bern, Switzerland

  • Laboratoire -Hematologie, Faculte de Pharmacie, Universite Paris Sud, Paris, France

Locations

  • France

  • Switzerland

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Musculoskeletal

Disease

  • Disseminated intravascular coagulation

  • Venous thrombosis

  • Hemophilia

  • Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis

Biomarkers

  • Adenomatous Polyposis Coli

  • Nucleoside diphosphate kinase A

  • Coagulation Factor III, Tissue Factor

  • Protein S

  • Tissue factor pathway inhibitor

  • Activated partial thromboplastin time

Drug/Treatment

  • FVIII

  • Fibrinogen (IV)

  • Protein C

  • folitixorin calcium

  • Evithrom

  • rFVIII

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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