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1663 : Stable Expression Of Chimeric Antigen Receptors (CARs) By Sleeping Beauty-Mediated Gene Transfer and Efficient Expansion Of Leukemia-Specific Cytokine-Induced Killer (CIK) Cells

Researchers

Presenter

  • Chiara Francesca Magnani

Principal Investigators

  • Nice Turazzi

  • Fabrizio Benedicenti

  • Greta Maria Paola Giordano Attianese

  • Sarah Tettamanti

  • Eugenio Montini

  • Laurence J N Cooper

  • Alessandro Aiuti

  • Andrea Biondi

  • Ettore Biagi

Medical Centers

  • San Raffaele-Telethon Institute for Gene Therapy (TIGET), Milan, Italy

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

  • San Raffaele-Telethon Institute for Gene Therapy (TIGET), Milan, Italy

  • Centro Ricerca Tettamanti, Clinica Pediatrica, Universit Milano Bicocca, Osp. San. Gerardo/Fondazione MBBM, Monza, Italy

  • Clinica Pediatrica, Universit degli studi di Milano-Bicocca, Fondazione MBBM/Ospedale S. Gerardo, Monza, Italy

Locations

  • United States

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Peripheral blood mononuclear cell

  • T-cell receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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