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1993 : Lenalidomide/Melphalan / Dexamethasone Chemotherapy In 50 Patients With Newly Diagnosed Amyloid Light Chain Amyloidosis: First Results Of a Prospective Single Center Phase 2 Study (Leomex)

Researchers

Presenter

  • Stefan O Schonland

Principal Investigators

  • Tilmann Bochtler

  • Axel Benner

  • Marianne Gawlik

  • Christoph Kimmich

  • Arnt V Kristen

  • Jorg Beimler

  • Anthony D. Ho

  • Ute Hegenbart

Medical Centers

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Medical Dept, Amyloidosis Center, Heidelberg, Germany

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Amyloidosis Center, University of Heidelberg, Heidelberg, Germany

  • Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany

  • Dept. of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

  • Division of Biostatistics, DKFZ, Heidelberg, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • AL Amyloidosis

  • Deep vein thrombosis

  • Diabetic neuropathy

  • Cardiac amyloidosis

  • Acute renal failure

  • Renal insufficiency

  • Amyloid disease

  • Neutropenia

  • Peripheral neuropathy

  • Venous thrombosis

Biomarkers

  • Circulating tumor cells

  • Creatinine

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Lenalidomide

  • Melphalan

Outcome

  • N/A


Study Design

  • N/A

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim