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1458 : Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo

Researchers

Presenter

  • Farideh Miraki-Moud

Principal Investigators

  • Linda Ariza-McNaughton

  • Essam A Ghazaly

  • David C Taussig

  • Katharine A Hodby

  • Phuong Luong

  • Andrew Clear

  • Fareeda Sohrabi

  • John Bomalaski

  • John Gribben

  • Dominique Bonnet

  • Peter Szlosarek

Medical Centers

  • Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

  • Haematopoietic Stem Cell Laboratory, Cancer Research UK, London, United Kingdom

  • Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

  • Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

  • Centre for Haemato-Oncology, Barts Cancer, London, United Kingdom

  • Haematopoietic Stem Cell Laboratory, Cancer Research UK, London Research Institute, London, United Kingdom

Locations

  • United Kingdom

Companies

  • Polaris Pharmaceutic

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Solid malignancies

Biomarkers

  • Argininosuccinate Synthase 1

Drug/Treatment

  • Interleukin

  • Cytarabine liposomal

  • Pegargiminase

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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