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1436 : New Design Of Human T-ALL Transplantation In NSG Mice Uncovers The Major Role Of CD31/PECAM1 In The Central Nervous System Infiltration

Researchers

Presenter

  • Sandrine Poglio

Principal Investigators

  • Anne-Laure Bauchet

  • Jose Ramon Pineda

  • Caroline Deswarte

  • Thierry Leblanc

  • Andre Baruchel

  • Paola Ballerini

  • Judith Landman-Parker

  • Iannis Aifantis

  • Francois Boussin

  • Francoise Pflumio

Medical Centers

  • MIRCEN, INSERM/CEA, Fontenay-aux-Roses, France

  • Pediatric Hematology and Oncology Department, Trousseau Hospital - APHP and UPMC Univ Paris 06, Paris, France

  • LSHL, IRCM, Inserm U, CEA, Fontenay-aux-Roses, France

  • Pediatric Hematology and Oncology Department, Trousseau Hospital - APHP and UPMC Univ Paris 06, Paris, France

  • Universite Paris Descartes, Paris, France

  • LRP, IRCM, CEA, Fontenay-aux-Roses, France

  • Pediatric Hematology and Immunology Department, Robert Debre hospital, APHP, Paris, France

  • Department of Systems Biology and Howard Hughes Medical Institute, New York, NY

  • UPMC Univ Paris 6, Paris, France

Locations

  • France

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • C-C Motif Chemokine Receptor 7

  • Cluster of Differentiation 25

  • Cluster of Differentiation 31

  • Interleukin-15

Drug/Treatment

  • IL-15

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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