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1433 : Overcoming Apoptosis Resistance In High Risk Acute Lymphoblastic Leukemia By Smac Mimetics In a Preclinical ALL Xenograft Model In Vivo

Researchers

Presenter

  • Melanie Schirmer

Principal Investigators

  • Manon Queudeville

  • Luca Trentin

  • Sarah M Eckhoff

  • Lueder H Meyer

  • Klaus-Michael Debatin

Medical Centers

  • Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany

  • Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Nuclear factor kappa-light-chain-enhancer of activated B cells

  • Breakpoint Cluster Region

  • Cluster of Differentiation 47

  • TNF Receptor Superfamily Member 1B

Drug/Treatment

  • TL32711

  • Etanercept

  • CHS-0214

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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