// App-Quantinova.ai

1431 : CD22-Targeted Chimeric Antigen Receptor (CAR) T Cells Containing The 4-1BB Costimulatory Domain Demonstrate Enhanced Persistence and Superior Efficacy Against B-Cell Precursor Acute Lymphoblastic Leukemia (ALL) Compared To Those Containing CD28

Researchers

Presenter

  • Waleed Haso

Principal Investigators

  • Haiying Qin

  • Ling Zhang

  • Rimas J Orentas

  • Terry J Fry

Medical Centers

  • Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

Biomarkers

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

  • Galectin-3

  • Interleukin-2

Drug/Treatment

  • OKT3

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim