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1430 : Transdifferentiation Of Primary Human Philadelphia Chromosome-Positive B Cell Acute Lymphoblastic Leukemia Cells Into Non-Leukemic Macrophages

Researchers

Presenter

  • James S. McClellan

Principal Investigators

  • Andrew J. Gentles

  • Christine E. Ryan

  • Ravi Majeti

Medical Centers

  • Center for Cancer Systems Biology, Stanford University, Stanford, CA

  • Department of Medicine, Division of Oncology, Stanford University, Stanford, CA

  • Department of Medicine, Division of Hematology, Cancer Center and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA

  • Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA

  • Cancer Center and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • CCAAT enhancer binding protein alpha

  • Cluster of Differentiation 11c

  • Cluster of Differentiation 14

  • Cluster of Differentiation 19

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim