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1428 : Inhibition Of The Wnt Pathway Leads To Improved Chemosensitivity In Pediatric Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Smita C. Dandekar

Principal Investigators

  • Eleny Romanos-Sirakis

  • Faye Pais

  • William L. Carroll

  • Teena Bhatla

  • Courtney L Jones

  • Wallace Bourgeois

  • Stephen P. Hunger

  • Elizabeth A. Raetz

  • Michelle L. Hermiston

  • Ramanuj Dasgupta

  • Debra J. Morrison

Medical Centers

  • Pediatric Hematology/Oncology/BMT, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO

  • Laura and Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY

  • Department of Pediatric Hematology-Oncology, New York University Medical Center, New York, NY

  • Pediatric Hematology/Oncology, NYU Cancer Institute, New York, NY

  • Cancer Institute, New York University, New York, NY

  • Cancer Institute, NYU Langone Medical Center, New York, NY

  • University of California, San Francisco, San Francisco, CA

  • University of California, San Francisco, San Francisco, CA

  • New York University Cancer Institute, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • B-cell acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • axin 2

  • Baculoviral IAP repeat-containing protein5

  • Nucleoside diphosphate kinase A

Drug/Treatment

  • Prednisolone

  • Doxorubicin

  • Cytarabine liposomal

  • Etoposide

  • Etoposide phosphate

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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