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1386 : Accumulation Of Gene Alterations Of TP53, Crebbp and IKZF1 Is a Prognostic Factor In Adult Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Kenji Tokunaga

Principal Investigators

  • Shunichro Yamaguchi

  • Taizo Shimomura

  • Hitoshi Suzushima

  • Yutaka Okuno

  • Hiroaki Mitsuya

  • Norio Asou

Medical Centers

  • Department of Pathology, Kumamoto Shinto General Hospital, Kumamoto City, Japan

  • Department of Hematology, International Medical Center, Saitama Medical University, Hidaka, Japan

  • Department of Hematology, Kumamoto University School of Medicine, Kumamoto, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Ph chromosome

  • CREB-binding protein

  • Embryonic ectoderm development

  • Enhancer of zeste homolog 2

  • Tumor protein p53

Drug/Treatment

  • TP53

  • EZH2

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim