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3971 : Pharmacological IGF1R/IRS Inhibitor, NT157, Effectively Induces Apoptosis and CDKN1A Expression in Acute Lymphoblastic Leukemia Cells

Researchers

Presenter

  • Ana Paula Nunes Rodrigues Alves

Principal Investigators

  • N/A

Medical Centers

  • Department of Internal Medicine, University of Sao Paulo at Ribeirao Preto School of Medicine, Ribeirao Preto, Brazil

Locations

  • Brazil

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Mitogen-activated protein kinase

  • Cyclin dependent kinase inhibitor 1A

  • Fms related tyrosine kinase 3 Ligand

  • Insulin receptor substrate 1

  • Insulin-like growth factor 1 receptor

  • Interleukin-7

Drug/Treatment

  • Linsitinib

  • NT157

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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