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3913 : The DNA-Binding Protein High Mobility Group Box 1 (HMGB1) Interacts with RelB to Maintain Non-Canonical NF-b Signaling, Cell Survival and Immune Evasion in Infant Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Liana M Toia

Principal Investigators

  • Jinno Antonio Magno

  • Jessica C Shand

Medical Centers

  • Division of Pediatric Hematology-Oncology, University of Rochester, Rochester, NY

  • University of Rochester Medcal Center, Rochester, NY

  • University of Rochester, Rochester, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Acute lymphoblastic leukemia

  • Sepsis

Biomarkers

  • Nucleoside diphosphate kinase A

  • High Mobility Group Box 1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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