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347 2016 ATVB : Endothelin-1 Regulates Molecules of the Major Histocompatibility Complex: Role in Sickle Cell Disease

Researchers

Presenter

  • Daniel Gil de Lamadrid

Principal Investigators

  • Analaura Santiago

  • Joshua Cazares

  • Shirley Valentin

  • Alicia Rivera

  • Jose R Romero

  • Yaritza Inostroza-Nieves

Medical Centers

  • Brigham & Women's Hospital, Boston, MA

  • San Juan Bautista School of Medicine, Caguas, PR

  • Brigham and Women's Hospital and Harvard Medical School, Boston, MA

  • Boston Children's Hospital, Harvard Medical School, Boston, MA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Sickle cell anemia

  • Venous thrombosis

Biomarkers

  • Endothelin-1

  • Human Leukocyte Antigen – DR isotype

  • Human leukocyte antigen A2

  • Major histocompatibility complex, class II, DR beta 1

  • Stearoyl-CoA desaturase

Drug/Treatment

  • endothelin-1

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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