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1056 : PP2A Balances Glucose Metabolism and Foxo Activation to Maintain Cellular Redox Homeostasis in Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Gang Xiao

Principal Investigators

  • Zhengshan Chen

  • Brass Daniel

  • Lai N Chan

  • Huimin Geng

  • Xiaoyan Jiang

  • Markus Muschen

Medical Centers

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • Metabolomics and Proteomics Center, University of California Los Angeles, Los Angeles, CA

  • Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • p53

  • Histone H2AX

Drug/Treatment

  • LB-100

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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