// App-Quantinova.ai

907 : Oncogenic Feedback Activation Between BCL6 and MLL Promotes Malignant Transformation in MLL -Rearranged Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Christian Hurtz

Principal Investigators

  • Lai N Chan

  • Erica Ballabio

  • Cheryl L. Willman

  • William L. Carroll

  • Scott A. Armstrong

  • Patricia Ernst

  • Ari Melnick

  • Thomas Milne

  • Markus Muschen

Medical Centers

  • Division of Hematology and Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

  • Department of Hematology/Oncology, Weill Cornell Medicine, New York, NY

  • Weatherall Institute of Molecular Medicine and Oxford Cancer Centre, Oxford, United Kingdom

  • Division of Pediatric Hematology Oncology, Department of Pediatrics, Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY

  • Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY.

  • University of New Mexico Cancer Center, Albuquerque, NM

  • MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • University of Colorado Cancer Center, Aurora, CO

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Vincristine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

Copyright © 2026. QuantiNova All rights reserved