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633 : Thrombosis in Myeloproliferative Neoplasms Is Linked to Increased Neutrophil Extracellular Trap (NET) Formation

Researchers

Presenter

  • Ofir Wolach

Principal Investigators

  • Rob S Sellar

  • Kimberly Martinod

  • Rebekka K. Schneider

  • Robert F. Padera

  • Ann Mullally

  • Denisa D. Wagner

  • Benjamin L. Ebert

  • Marie E. McConkey

  • Alexander J. Silver

  • Ryan Chappell

  • Richard M. Stone

  • Martha Wadleigh

  • David P Steensma

  • Daniel J. DeAngelo

  • Ilene Galinsky

Medical Centers

  • Program in Cellular and Molecular Medicine, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA

  • Department of Medicine, Brigham and Women's Hospital, Boston, MA

  • Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA

  • Department of Medicine, Brigham and Women's Hospital, Boston, MA

  • Dana-Farber Cancer Institute, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myeloid neoplasms

  • Venous thrombosis

  • Twin-reversed arterial perfusion

Biomarkers

  • N/A

Drug/Treatment

  • Ruxolitinib phosphate

  • lonomycin

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim