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455 : Whole Exome Sequencing of Pediatric Acute Lymphoblastic Leukemia Patients Identify Mutations in 11 Pathways: A Report from the Children's Oncology Group

Researchers

Presenter

  • Mignon L. Loh

Principal Investigators

  • Deqing Pei

  • Richard C. Harvey

  • Nyla A. Heerema

  • Ilaria Iacobucci

  • Deborah Payne

  • Kelly W. Maloney

  • Eric Larsen

  • Elizabeth Raetz

  • Cheryl L. Willman

  • Naomi Winick

  • William L. Carroll

  • Yunfeng Dai

  • Charles G. Mullighan

  • Stephen P. Hunger

  • Xiaotu Ma

  • Meenakshi Devidas

  • Michael Edmondson

  • Michael Rusch

  • Andrew J. Carroll

  • I-Ming Chen

  • Julie Gastier-Foster

Medical Centers

  • Center for Cancer and Blood Disorders, Childrens Hospital Colorado, Aurora, CO

  • Department of Chemical Biology and Therapeutics, St. Jude Childrens Research Hospital, Memphis, TN

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL

  • Division of Hematology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, OH

  • Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, and Departments of Pathology and Pediatrics, Ohio State University, Columbus, OH

  • Department of Pathology, The Cancer Research and Treatment Center, University of New Mexico, Albuquerque, NM

  • Dept of Biostatistics, Colleges of Medicine, Public Health & Health Professions, University of Florida, Gainsville, FL

  • St. Jude Children's Research Hospital, Memphis, TN

  • University of New Mexico Cancer Center, Albuquerque, NM

  • Department of Pediatrics, Huntsman Cancer Institute and Primary Childrens Hospital, University of Utah, Salt Lake City, UT

  • St. Jude Children's Research Hospital, Memphis, TN

  • Division of Pediatric Hematology Oncology, Department of Pediatrics, Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY

  • Department of Pediatrics and the Center for Childhood Cancer Research, Childrens Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Dept. of Pediatrics and the Hellen Diller Family Comprehensive Cancer Center, Benioff Children's Hospital, University of California at San Francisco, San Francisco, CA

  • University of New Mexico Cancer Center, Albuquerque, NM

  • Pediatrics (Hem/Onc and ID) and Microbiology, University of Texas Southwestern Medical Center, Dallas, TX

  • Maine Childrens Cancer Program, Scarborough, ME

  • Department of Biostatistics, University of Florida, Gainesville, FL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • White Blood Cell

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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