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452 : Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Qiao-Yang Sun

Principal Investigators

  • Kar-Tong Tan

  • Manoj Garg

  • Yan-Yi Jiang

  • Liang Xu

  • Su-Lin Lim

  • Li-Zhen Liu

  • Vikas Madan

  • Masashi Sanada

  • Lucia Torres Fernandez

  • Hema Preethi S.S

  • Michael Lill

  • Wenwen Chien

  • Hagop M. Kantarjian

  • Steven M. Kornblau

  • Satoru Miyano

  • Der-Cherng Liang

  • Seishi Ogawa

  • Lee-Yung Shih

  • Henry Yang

  • H. Phillip Koeffler

  • Anand Mayakonda

  • Allen Eng Juh Yeoh

  • Norihiko Kawamata

  • Yasunobu Nagata

  • Xiao Jin-Fen

  • Xin-Yi Loh

  • De-Chen Lin

Medical Centers

  • Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore

  • UCLA School of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

  • Cedars-Sinai Medical Center, Los Angeles, CA

  • Beckman Research Institute at City of Hope, Duarte, CA

  • Chang Gung Memorial Hospital, Division of Hematology-Oncology, Taipei, Taiwan

  • National University Cancer Institute of Singapore, Singapore, Singapore

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  • Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore

  • Department of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan

  • Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

  • Laboratory of DNA information Analysis & Laboratory of Sequence Analysis, Human Genome Center, The University of Tokyo, Tokyo, Japan

  • Division of Pediatric Hematology-Oncology, Mackay Children's Hospital and Mackay Medical College, Taipei, Taiwan

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

Locations

  • United States

  • Taiwan

  • Japan

  • Singapore

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • AT-rich interactive domain 1A

  • AT-rich interactive domain 2

  • Breakpoint Cluster Region

  • CREB-binding protein

  • E1A Binding Protein P300

  • Embryonic ectoderm development

  • Enhancer of zeste homolog 2

  • Tet methylcytosine dioxygenase 2

  • Sirtuin 1

  • Chromodomain-helicase-DNA-binding protein 4

Drug/Treatment

  • EP300

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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