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217 : Efficacy of Humanized CD19-Targeted Chimeric Antigen Receptor (CAR)-Modified T Cells in Children and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Shannon L Maude

Principal Investigators

  • Susan R. Rheingold

  • Regina M Young

  • John Scholler

  • Katherine T. Marcucci

  • Bruce L Levine

  • Noelle Frey

  • David L Porter

  • Simon F. Lacey

  • J. Joseph Melenhorst

  • Carl H June

  • Stephan A. Grupp

  • Richard Aplenc

  • David T Teachey

  • Colleen Callahan

  • Diane Baniewicz

  • Claire White

  • Mala K. Talekar

  • Pamela A Shaw

  • Jennifer L Brogdon

Medical Centers

  • Division of Oncology, Cancer Immunotherapy Program, Children's Hospital of Philadelphia, Philadelphia, PA

  • Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA

  • Childrens Hospital of Philadelphia, Philadelphia, PA

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

  • Division of Hematology/Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

Locations

  • United States

Companies

  • Novartis AG

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Coxsackie Virus And Adenovirus Receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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