// App-Quantinova.ai

175 : Randomized Study of Pegasparagase (SS-PEG) and Calaspargase Pegol (SC-PEG) in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: Results of DFCI ALL Consortium Protocol 11-001

Researchers

Presenter

  • Lewis B. Silverman

Principal Investigators

  • Sarah K. Hunt

  • Marshall A. Schorin

  • Maria Luisa Sulis

  • Jennifer J.G. Welch

  • Jeffrey G. Supko

  • Xiaoyong He

  • Sarah Hilderbrand

  • Andrew E. Place

  • Lynda M. Vrooman

  • Marian H. Harris

  • Kristen E. Stevenson

  • Samantha Kay-Green

  • Donna S. Neuberg

  • Stephen E. Sallan

  • Uma H. Athale

  • Luis A. Clavell

  • Peter D. Cole

  • Kara M. Kelly

  • Caroline Laverdiere

  • Jean-Marie Leclerc

  • Bruno Michon

Medical Centers

  • Inova Fairfax Hospital for Children, Falls Church, VA

  • Hematology-Oncology Division, Charles Bruneau Cancer Center, Sainte-Justine University Hospital, University of Montreal, Montreal, QC, Canada

  • Division of Hematology/Oncology, McMaster Children's Hospital, Hamilton Health Sciences, Hamilton, ON, Canada

  • Centre Hospitalier Universitaire de Quebec, Quebec City, QC, Canada

  • Dana-Farber/Harvard Cancer Center, Massachusetts General Hospital, Boston, MA

  • Roswell Park Cancer Institute, Buffalo, NY

  • San Jorge Childrens Hospital, Santurce, PR

  • Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

  • Boston Children's Hospital, Boston, MA

  • Division of Pediatric Hematology, Oncology and Stem Cell Transplant, Department of Pediatrics, Columbia University Medical Center, New York, NY

  • Department of Pathology, Texas Children's Hospital, Houston, TX

  • Dana-Farber Cancer Institute, Boston, MA

  • Montefiore Medical Center, Bronx, NY

  • Massachusetts General Hospital, Boston, MA

  • Pediatrics - Neonatology, CHU Sainte-Justine - Universite de Montreal, Montreal, Canada

  • Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Childrens Hospital, Boston, MA

  • Pediatric Hematology Oncology, Hasbro Children's Hospital/Brown University, Providence, RI

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Pancreatitis

  • Venous thrombosis

  • Lymphomas

Biomarkers

  • Breakpoint Cluster Region

  • Immunoglobulin heavy-chain variable region gene

  • Serum amyloid A

  • T-cell receptor

Drug/Treatment

  • Erwinase

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

Copyright © 2026. QuantiNova All rights reserved