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LBA-1 : Frequent Mutations in the Calreticulin Gene CALR in Myeloproliferative Neoplasms

Researchers

Presenter

  • Klampfl Thorsten

Principal Investigators

  • Ashot S Harutyunyan

  • Gregory I. Vladimer

  • Klaudia Bagienski

  • Chiara Milanesi

  • Ilaria Carola Casetti

  • Emanuela San-Antonio

  • Virginia Ferretti

  • Chiara Elena

  • Fiorella Schischlik

  • Ciara Cleary

  • Melanie Six

  • Harini Nivarthi

  • Martin Schalling

  • Andreas Schonegger

  • Christoph Bock

  • Luca Malcovati

  • Christiana Pascutto

  • Giulio Superti-Furga

  • Mario Cazzola

  • Robert Kralovics

  • Elisa Rumi

  • Jelena D. Milosevic

  • Nicole C.C. Them

  • Tiina Berg

  • Bettina Gisslinger

  • Daniela Pietra

  • Doris Chen

Medical Centers

  • Department of Clinical Medicine 3, University of Padova, Padova, Italy

  • Department of Hematology Oncology, IRCCS Policlinico S. Matteo Foundation and University of Pavia, Pavia, Italy

  • CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

  • Medical Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

  • Dept. of Medicine I, Div. of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria

Locations

  • Italy

  • Austria

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Chronic myelomonocytic leukemia

  • Myeloid neoplasms

  • Essential thrombocythemia

  • Alpha-thalassemia myelodysplasia syndrome

  • Chronic Myelogenous Leukemia

  • Acute myelocytic leukemia

  • Anemia

  • Polycythemia vera

  • Myelofibrosis

  • Venous thrombosis

Biomarkers

  • MPL proto-oncogene, thrombopoietin receptor

  • Calreticulin

  • Signal transducer and activator of transcription 5

Drug/Treatment

  • Interleukin

  • Fedratinib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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