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3809 : P190BCR-ABL1 Signaling Modulates The Function Of Tumor Suppressor Protein IKZF1

Researchers

Presenter

  • Marc Demkes

Principal Investigators

  • Edwin Lasonder

  • Edo Luijten

  • Peter M. Hoogerbrugge

  • Frank N. van Leeuwen

  • Blanca Scheijen

Medical Centers

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Laboratory of Pediatric Oncology, Radboud university medical center, Nijmegen, Nijmegen, Netherlands

  • Centre for Molecular and Biomolecular Informatics, Nijmegen Centre for Molecular Life Sciences, Nijmegen, Netherlands

  • Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands

Locations

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • BCL2 associated X, apoptosis regulator

  • Nucleoside diphosphate kinase A

Drug/Treatment

  • Doxycycline

  • Imatinib

  • IkT001

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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