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3796 : Loss Of Tumor Suppressor BTG1 Enhances ATF4 Function and Promotes Cell Survival

Researchers

Presenter

  • Laurens T. van der Meer

Principal Investigators

  • Laurensia Yuniati

  • Esther J.H. Tijchon

  • Liesbeth van Emst

  • Manon Alkema

  • Caroline Rodenbach

  • Blanca Scheijen

  • Peter M. Hoogerbrugge

  • Frank N. van Leeuwen

Medical Centers

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Laboratory of Pediatric Oncology, Radboud university medical center, Nijmegen, Nijmegen, Netherlands

  • Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands

Locations

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Nucleoside diphosphate kinase A

  • Cluster of differentiation 45

  • Protein Arginine Methyltransferase 1

Drug/Treatment

  • Asparaginase

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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