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3745 : Epigenetic Dysregulation Of ZNF423 Impedes B-Cell Differentiation and Is Linked To Adverse Outcome Of Childhood B-Precursor ALL

Researchers

Presenter

  • Ann-Christin Puller

Principal Investigators

  • Lena Harder

  • Martin Zimmermann

  • Carol Stocking

  • Martin A. Horstmann

Medical Centers

  • Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany

  • Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany

  • Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany

  • Research Institute Childrens Cancer Center and Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Nucleoside diphosphate kinase A

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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