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3737 : PU.1 and Spi-B Oppose Transformation Of Pre-B Cells Through Activation Of Key Genes Involved In B Cell Receptor Signalling

Researchers

Presenter

  • Darah A. Christie

Principal Investigators

  • Shereen A. Turkistany

  • Li S. Xu

  • Stephen K. H. Li

  • Ian Welch

  • Heather C. Broughton

  • Gillian I. Bell

  • David A. Hess

  • Rodney P. DeKoter

Medical Centers

  • Animal Care and Veterinary Medicine, University of Western Ontario, London, ON, Canada

  • Dept Microbiology and Immunology, University of Western Ontario, London, ON, Canada

  • Physiology & Pharmacology, University of Western Ontario, London, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Interleukin

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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