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3721 : Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Researchers

Presenter

  • Eva Moravcsik

Principal Investigators

  • Melanie Joannides

  • Edwige Voisset

  • Paolo Salomoni

  • Chi Wai Eric So

  • Scott C. Kogan

  • Ellen Solomon

  • David Grimwade

  • Eva Wessel Stratford

  • Bernd B. Zeisig

  • Jo Morris

  • Ruth Densham

  • Chris Palgrave

  • Gordon Stamp

  • Emma Nye

  • Robert K. Hills

Medical Centers

  • Kingston University London, London, United Kingdom

  • Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA

  • Oslo University Hospital, Oslo, Norway

  • Kings College London, London, United Kingdom

  • Medical and Molecular Genetics, Kings College, London, London, United Kingdom

  • Kings College London, London, United Kingdom

  • Kings College London, London, United Kingdom

  • CRUK London Research Institute, London, United Kingdom

  • School of Medicine, Department of Haematology and Institute of Translation Innovation Methodology & Engagement, Cardiff University, Cardiff, United Kingdom

  • Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom

  • Medical and Molecular Genetics, Kings College, London, London, United Kingdom

  • University of Birmingham, Birmingham, United Kingdom

Locations

  • United States

  • United Kingdom

  • Norway

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute promyelocytic leukemia

  • Acute lymphoblastic leukemia

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • Promyelocytic Leukemia

  • Histone H2AX

Drug/Treatment

  • Cysteine Hydrochloride

  • T-15

  • Tretinoin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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