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3575 : Increased Thrombin Generation and Fibrin Formation In Premature Aging BMAL1 Deficient Mice

Researchers

Presenter

  • Marisa Ninivaggi

Principal Investigators

  • Hilde Kelchtermans

  • Marijke Kuipers

  • Bianca Hemmeryckx

  • Johan Heemskerk

  • Theo Lindhout

  • Marc F. Hoylaerts

  • Bas De Laat

Medical Centers

  • Synapse BV, CARIM, Maastricht University, Maastricht, Netherlands

  • Center for Molecular and Vascular Biology, Katholieke Universiteit Leuven, Leuven, Belgium

  • Department of Biochemistry, CARIM, Maastricht University, Maastricht, Netherlands

  • Department of Biochemistry, CARIM, Maastricht University, Maastricht, Netherlands

  • Synapse BV, Maastricht, Netherlands

Locations

  • Belgium

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Aryl hydrocarbon receptor nuclear translocator-like protein 1

  • Catalase

  • ZFP36 Ring Finger Protein Like 1

Drug/Treatment

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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