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617 : Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1-Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

Researchers

Presenter

  • Virginia Perez-Andreu

Principal Investigators

  • Richard C. Harvey

  • Yiping Fan

  • Meenakshi Devidas

  • Michael J. Borowitz

  • Colton Smith

  • Geoffrey A. Neale

  • Esteban Gonzalez Burchard

  • Dara G Torgerson

  • Federico Antillon

  • Cesar Rolando

  • Naomi J. Winick

  • Wenjian Yang

  • Bruce Camitta

  • Elizabeth A. Raetz

  • Brent L. Wood

  • Feng Yue

  • William L. Carroll

  • Eric C. Larsen

  • William Paul Bowman

  • Mignon L. Loh

  • Michael Dean

  • Deepa Bhojwani

  • Cheng Cheng

  • Ching-Hon Pui

  • William E. Evans

  • Mary V. Relling

  • Stephen P. Hunger

  • Cheryl L. Willman

  • Charles G. Mullighan

  • Jun J. Yang

  • Deqing Pei

  • Heng Xu

  • Julie Gastier-Fostier

  • Shuyu E

  • Joshua Yew-Suang Lim

  • I-Ming L. Chen

Medical Centers

  • Pediatric Hematology/Oncology/BMT, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO

  • University of New Mexico Cancer Center, Albuquerque, NM

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Oncology, Johns Hopkins University, Baltimore, MD

  • St. Jude Children's Research Hospital, Memphis, TN

  • Pediatric Hematology/Oncology, NYU Cancer Institute, New York, NY

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX

  • Neonatology, Benioff Childrens Hospital, University of California San Francisco, San Francisco, CA

  • Cancer Center/Pathology, University of New Mexico, Albuquerque, NM

  • Department of Laboratory Medicine, University of Washington, Seattle, WA

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Maine Childrens Cancer Program, Scarborough, ME

  • Cancer Institute, New York University, New York, NY

  • St. Jude Children's Research Hospital, Memphis, TN

  • Unidad Nacional de Oncologia Pediatrica, Guatemala City, Guatemala

  • Hartwell Center for Bioinformatics and Biotechnology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Department of Radiology, Cook Childrens Medical Center, Fort Worth, TX

  • Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN

  • Medical College of Wisconsin, Wauwatosa, WI

  • Dept of Biostatistics, Colleges of Medicine, Public Health & Health Professions, University of Florida, Gainsville, FL

Locations

  • United States

  • Guatemala

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • GATA Binding Protein 3

  • Janus kinase

  • Thiopurine S-methyltransferase

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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