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544 : Phase II Trial Of Medium-Dose VP-16, Cyclophosphamide and Total-Body Irradiation Conditioning Regimen Before Allogeneic Stem Cell Transplantation For Acute Lymphoblastic Leukemia In Adults

Researchers

Presenter

  • Tatsunori Goto

Principal Investigators

  • Akio Shigematsu

  • Makoto Onizuka

  • Koichi Miyamura

  • Takahiro Fukuda

  • Yasuo Morishima

  • Masahiro Imamura

  • Shin Fujisawa

  • Ritsuro Suzuki

  • Yoshiko Atsuta

  • Kazuo Hatanaka

  • Masayoshi Masuko

  • Toshiro Ito

  • Naoki Kobayashi

  • Jun Kato

Medical Centers

  • Department of HSCT Data Management/Biostatistics, Nagoya University Graduate School of Medicine, Nagoya, Japan

  • Department of Pathologic Oncology, Mie University Graduate School of Medicine, Mie, Japan

  • Department of Pediatrics, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan

  • Department of Hematology, Yokohama City University Medical Center, Yokohama, Japan

  • Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital,

  • Department of Hematology, Hokkaido University, Sapporo, Japan

  • Department of Medical Oncology, Kyorin University School of Medicine, Tokyo, Japan

  • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan

  • Department of Gastroenterology, Sapporo Hokuyu Hospital, Sapporo, Japan

  • Department of Hematology and Cell Therapy, Aichi Cancer Center, Nagoya, Japan

  • Department of Dermatology, Wakayama Medical University, Wakayama, Japan

  • Japanese Red Cross Nagoya First Hospital, Nagoya, Japan

  • Department of Stem Cell Transplantation, Niigata University Medical and Dental Hospital, Niigata, Japan

  • Department of Radiology, Shinshu University School of Medicine, Matsumoto, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Acute lymphoblastic leukemia

  • Graft-versus-host disease

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Breakpoint Cluster Region

  • Ph chromosome

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • Etoposide phosphate

  • Allopurinol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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