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459 : The First Report Of Differences In Fibrin Clot Nanostructure and Response To Tissue Plasminogen Activator (TPA) and Unfractionated Heparin (UFH) In Infants Compared To Adults

Researchers

Presenter

  • Vera Ignjatovic

Principal Investigators

  • Leonie Pelkmans

  • Saartje Bloemen

  • Vasiliki Karlaftis

  • Chantal Attard

  • Raed Al Dieri

  • Bas De Laat

  • Paul Monagle

Medical Centers

  • Department of Physiotherapy, The University of Melbourne, Parkville, Australia

  • Rheumatology, Royal Childrens Hospital, Parkville, Australia

  • Synapse BV, CARIM, Maastricht University, Maastricht, Netherlands

  • Synapse BV, CARIM, Maastricht University, Maastricht, Netherlands

  • Haematology Research, Murdoch Childrens Research Institute, Parkville, Australia

  • Department of Biochemistry, CARIM, Maastricht University, Maastricht, Netherlands

Locations

  • Australia

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Serpin E1

  • Thrombin-activatable fibrinolysis inhibitor

  • Translocator protein

Drug/Treatment

  • Heparin

  • Evithrom

  • Heparin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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